IONIS PHARMACEUTICALS INC IONS

Latest FY: 2025 Healthcare Biotechnology
Market Price $55.62
Market Cap $9.19B
P/E Ratio N/A
Quick Peer Compare (Healthcare):
Revenue (FY 2025) ↑33.8% YoY
$943.71M
3-Yr CAGR: 17.1%
Net Income ↑16.0% YoY
-$381.39M
Net Margin: -40.4%
Free Cash Flow ↑41.4% YoY
-$320.03M
FCF Yield: -3.48%
EPS (Diluted) ↑21.7% YoY
$-2.38
Basic: $-2.38
Return on Equity Efficiency
-78.0%
ROA: -10.8%

📊 Multi-Year Historical Performance & Trends

Financial Performance History Revenue, Net Income & Free Cash Flow
Margins Trend (%) Gross, Operating & Net Margins
Balance Sheet Strength Cash, Debt & Equity
Cash Flow Generation Operating Cash Flow vs CapEx vs FCF

📈 Year-over-Year (YoY) Growth History (IONS)

All monetary values in millions ($M)
Fiscal Year Revenue Revenue YoY Gross Profit Net Income Net Inc YoY Diluted EPS EPS YoY Div / Sh Div Yield Op. Cash Flow Free Cash Flow FCF YoY
FY 2016 $346.6M $307.8M $-86.6M 0.00% $-112.1M $-119.2M
FY 2017 $507.7M +46.5% $462.9M $-6.0M +93.1% $0.08 0.00% $174.1M $139.4M +216.9%
FY 2018 $599.7M +18.1% $554.9M $273.7M +4,685.3% $2.07 +2,487.5% 0.00% $602.9M $589.3M +322.8%
FY 2019 $1,122.6M +87.2% $1,073.8M $294.1M +7.5% $2.08 +0.5% 0.00% $345.7M $314.8M -46.6%
FY 2020 $729.3M -35.0% $684.3M $-451.3M -253.4% $-3.23 -255.3% 0.00% $35.9M $0.8M -99.8%
FY 2021 $810.5M +11.1% $799.6M $-28.6M +93.7% $-0.20 +93.8% 0.00% $30.8M $18.8M +2,340.9%
FY 2022 $587.4M -27.5% $573.3M $-269.7M -843.2% $-1.90 -850.0% 0.00% $-274.4M $-290.1M -1,639.4%
FY 2023 $787.6M +34.1% $775.0M $-366.3M -35.8% $-2.56 -34.7% 0.00% $-307.5M $-331.3M -14.2%
FY 2024 $705.1M -10.5% $688.1M $-453.9M -23.9% $-3.04 -18.8% 0.00% $-500.9M $-546.2M -64.9%
FY 2025 $943.7M +33.8% $926.4M $-381.4M +16.0% $-2.38 +21.7% 0.00% $-268.6M $-320.0M +41.4%
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Valuation

Market Price $55.62
Market Cap $9.19B
Enterprise Value $10.58B
P/E Ratio N/A
P/B Ratio 18.79
FCF Yield -3.48%
Dividend Yield N/A
Shares Outstanding 165,262,600
%

Profitability & Margins

Gross Margin 98.17%
Operating Margin -40.45%
Net Margin -40.41%
Return on Equity (ROE) -77.98%
Return on Assets (ROA) -10.82%
Asset Turnover 0.27x
Revenue 3-Yr CAGR 17.12%
🛡️

Financial Health & Liquidity

Current Ratio 3.83
Cash Ratio 0.48
Debt / Equity 3.599
Debt / Assets 0.499
Cash & Equivalents $372.26M
Total Debt $1.76B
Book Value / Share $2.96
💧

Cash Flow Efficiency

Operating Cash Flow -$268.58M
Capital Expenditures (CapEx) $51.44M
Free Cash Flow -$320.03M
OCF / Revenue -28.46%
FCF / Revenue -33.91%
FCF 3-Yr CAGR N/A
🏷️

Per Share Metrics

EPS (Diluted) $-2.38
EPS (Basic) $-2.38
Dividends / Share N/A
Book Value / Share $2.96
EPS YoY Growth 21.71%
🏛️

Balance Sheet (FY 2025)

Total Assets $3.52B
Total Liabilities $3.03B
Stockholders' Equity $489.09M
Current Assets $2.99B
Current Liabilities $781.57M